2015-06-03 17:49:27 UTC

Microscopic Esophagitis

Clinical Snapshots


This AGA Clinical Snapshot is an executive summary of Drs. Chang and Moawad's presentation during the 2015 AGA Spring Postgraduate Course at DDW® 2015 in Washington, DC.

Clinical snapshots are free to AGA members. Please log in and "purchase" the free module to add it to your account. You will then have access to the full content of the summary on this same page whenever you are logged into the website.


1. Understand the similarities and differences between GERD, PPI-responsive eosinophilic esophagitis (REE) and eosinophilic esophagitis (EoE).

2. Understand the mechanism of PPI response in PPI-REE patients.

3. Recognize that PPI is first-line treatment in patients with esophageal eosinophilia.

About the Instructors

Edaire Cheng, MD, UT Southwestern Pediatric Gastroenterology

Fouad Moawad, MD, FACP, FACG Walter Reed National Military Medical Center

This is only a preview. Full access is reserved for AGA members. Login or learn more about becoming a member.

Eosinophils in the Esophagus

In the early 1980s, esophageal eosinophilia was once regarded as a histologic feature of GERD and correlated with abnormal acid clearance determined by esophageal pH monitoring. Eosinophils were found in all levels of the esophagus, and involvement of the proximal esophagus was associated with greater abnormalities in the pH studies. In the 1990s, case series involving dense esophageal eosinophilia in atopic individuals with dysphagia and normal pH monitoring introduced the idea of eosinophilic esophagitis as an emerging entity distinct from GERD. By 2001, several case reports underscored the diagnostic confusion between GERD and EoE and demonstrated the need for clear diagnostic criteria …

More on Eosinophilic Esophagitis

Course for APPs benefits all experience levels

April 16, 2018

AGA's popular course for advanced practice providers will take place Aug. 10 through 12 in Chicago, Illinois.

APPs: Enhance your delivery of patient care

March 28, 2018

AGA's popular course for advanced practice providers will be held this summer in Chicago.

Blog: Prick Test to Identify Allergens That Cause Esophageal Sensitization

Jan. 17, 2018

Researchers developed an esophageal prick test, in which the esophageal mucosa is challenged by local injection of allergen extracts. Read more on the AGA Journals Blog.